14.01.2025.
Starting November 1, 2025, the European Commission is introducing new rules for cosmetics containing retinol and its derivatives. Why? Because while these powerful ingredients can transform your skin, they can also cause side effects like dryness and peeling if not used correctly.
Let’s break it all down and see what this means for you.
Understanding Vitamin A, Retinol, and Retinoids in aesthetic medicine
Vitamin A is like the MVP of skincare. It’s fat-soluble, meaning your body stores it, and it’s essential for keeping your skin healthy and glowing. Retinol and retinoids, two Vitamin A derivatives, are superstars in the anti-aging and skin-rejuvenation world. But what’s the difference?
- Retinol: Think of it as the gentle giant. It’s commonly found in over-the-counter products and works slowly, converting into retinoic acid when applied to your skin. It’s perfect for beginners or those with sensitive skin.
- Retinoids: These are the heavy hitters. Prescription-strength versions like tretinoin or isotretinoin deliver faster, stronger results but need a doctor’s guidance because they can be intense.
Both work by speeding up cell turnover, boosting collagen, and tackling wrinkles and uneven skin tone. But retinoids are more potent, which is why they come with a risk of dryness and irritation.
New rules for retinol fans

Under the new European Commission guidelines, products with retinol, retinyl acetate, or retinyl palmitate will need to carry a warning label: “Contains Vitamin A. Consider your daily intake before use.” This isn’t just a suggestion; it’s about keeping you safe. Vitamin A can build up in your liver over time, and too much can be harmful.
Here’s what the World Health Organization (WHO) recommends for daily Vitamin A intake:
- Adults: 700-900 mcg per day
- Pregnant Women: Up to 770 mcg per day
Different forms, same purpose
- PurposeRetinol: The purest form of Vitamin A, it’s a go-to for reducing wrinkles and boosting collagen. But beware – it’s sensitive to light and air, so it needs special packaging.
- Retinyl Acetate: A gentler form that’s great for sensitive skin or first-timers. It converts to retinol and retinoic acid after it’s absorbed.
- Retinyl Palmitate: The mildest of the bunch. It’s less powerful but perfect for maintaining results or for super-sensitive skin.
Why does this matter to you?
If you love retinol for its anti-aging properties or acne-fighting powers, don’t panic! These rules are about safety, not banning. Here are some tips to keep your skin glowing:
Get Professional Advice: A dermatologist or aesthetic doctor can help you choose the right product and strength for your skin type and goals.
Start Slow: If you’re new to retinol, ease into it. Use it a couple of times a week and build up as your skin adjusts.
Hydrate, Hydrate, Hydrate: Retinol can be drying, so pair it with a good moisturizer to keep your skin happy.
The bottom line
Vitamin A-based skincare is a game-changer, but it’s powerful stuff. With the new regulations, you’ll have clear labels and guidelines to help you make informed choices.
Under the guidance of a qualified aesthetic doctor or a dermatologist, Vitamin A-based treatments are both safe and effective.
A trained professional can assess the patient’s skin type, history, and goals to recommend the appropriate derivative, concentration, and regimen.
This approach minimizes risks such as dryness or irritation while delivering tailored results.
Beyond treating conditions like acne, these treatments are widely utilized for cosmetic purposes such as anti-aging and overall skin care.
In the hands of a skilled medical aesthetician, even the most potent forms, like Retinol, can be safely incorporated into a personalized plan, striking the right balance between safety and efficacy while maintaining skin health.
SOURCES
Newstalk – Retinol and European Commission Restrictions Beauty product Retinol to be limited by European Commission
Official Journal of the European Union European Commission Official Regulation on Retinol
World Health Organization (WHO) Vitamin and Mineral Requirements in Human Nutrition
American Academy of of Dermatology – Retinol and Retinoids Retinoids Overview

Walter Castorina, MD
Lecturer in Anatomy
Aesthetic Physician




